Purpose

• To provide user-friendly access to state-of-the-art equipment, service and expertise in electron microscopy to the IUB campus and beyond.
• To promote the development of researchers that are knowledgeable, confident and comfortable in the use of electron microscopes.

Facility

• Microscopes: JEOL JEM 1010, JEOL JEM 1400plus, JEOL JEM 3200FS, Thermo-Fisher Teneo SBFI-SEM, Thermo-Fisher Talos Arctica cryo-EM and JEOL JEM NEOARM.
• Microscope techniques: transmission electron microscopy (TEM), scanning transmission electron microscopy (STEM), TEM and STEM tomography, high resolution transmission electron microscopy (HRTEM), energy filtered transmission electron microscopy (EFTEM), cryoTEM, SEM, Serial Block-Face Imaging (SBFI), EDX, STEM/EDX and STEM/EELS.

• in situ TEM holders for both heating and multi-port liquid cell studies.
• Sample preparation equipment includes ultramicrotomes, a high-pressure freezer, a freeze substitution robot, automated and manual plunge freezers, carbon coater, glow discharge devices and a sputter coater.
• Image processing and analysis workstations and software.

Services

• Consultation on experimental design for the best use of electron microscopes.
• Fee-for-service work in all aspects of electron microscopy.
• Training of new-users in sample preparation, microscope operation, and data analysis.
• Annual graduate course on biological electron microscopy.